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4 results

  • 5 - Cellular and molecular mechanisms of associative and nonassociative learning

  • from Section A1 - Cellular and molecular mechanisms of neural plasticity
    • By John H. Byrne, Department of Neurobiology and Anatomy, University of Texas Health Science Center at Houston, Houston, TX, USA, Diasinou Fioravante, Department of Neurobiology and Anatomy, University of Texas Health Science Center at Houston, Houston, TX, USA, Evangelos G. Antzoulatos, Department of Neurobiology and Anatomy, University of Texas Health Science Center at Houston, Houston, TX, USA
  • Edited by Michael Selzer, University of Pennsylvania, Stephanie Clarke, Université de Lausanne, Switzerland, Leonardo Cohen, National Institute of Mental Health, Bethesda, Maryland, Pamela Duncan, University of Florida, Fred Gage, Salk Institute for Biological Studies, San Diego
  • Book:
    Textbook of Neural Repair and Rehabilitation
    Published online:
    05 March 2012
    Print publication:
    16 February 2006, pp 79-94

  • Summary

    The neural mechanisms that contribute to the adaptation of an organism to environmental changes through learning are likely to contribute to the adaptation of the organism to physical changes (e.g., trauma) through repair and rehabilitation. Learning can be distinguished depending on whether it is associative or nonassociative. The examination of learning in simple model systems, such as the marine mollusc Aplysia californica, has proven to be very fruitful. The simplicity and tractability of the neural circuits mediating some behaviors in Aplysia have allowed the cellular/molecular dissection of the underlying neural mechanisms. Indeed a number of critical cells, synapses, and molecules have been identified in Aplysia to mediate basic forms of learning. One way to recruit the processes of neuronal plasticity in repair and rehabilitation is through behavioral learning paradigms, which provide the basis for current therapeutic strategies.