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Selective detection of folic acid in the midst of other biomolecules using water-soluble AgInS2 quantum dots

Published online by Cambridge University Press:  16 September 2019

Bambesiwe M.M. May ,
Sundararajan Parani ,
Jose Varghese Rajendran  and
Oluwatobi S. Oluwafemi
Bambesiwe M.M. May
Affiliation:
Department of Chemical Sciences (formerly Applied Chemistry), University of Johannesburg, P.O. Box 17011, Doornfontein, 2028Johannesburg, South Africa Centre for Nanomaterials Science Research, University of Johannesburg, Doornfontein, South Africa
Sundararajan Parani
Affiliation:
Department of Chemical Sciences (formerly Applied Chemistry), University of Johannesburg, P.O. Box 17011, Doornfontein, 2028Johannesburg, South Africa Centre for Nanomaterials Science Research, University of Johannesburg, Doornfontein, South Africa
Jose Varghese Rajendran
Affiliation:
Department of Chemical Sciences (formerly Applied Chemistry), University of Johannesburg, P.O. Box 17011, Doornfontein, 2028Johannesburg, South Africa Centre for Nanomaterials Science Research, University of Johannesburg, Doornfontein, South Africa
Oluwatobi S. Oluwafemi*
Affiliation:
Department of Chemical Sciences (formerly Applied Chemistry), University of Johannesburg, P.O. Box 17011, Doornfontein, 2028Johannesburg, South Africa Centre for Nanomaterials Science Research, University of Johannesburg, Doornfontein, South Africa
*
Address all correspondence to Oluwatobi S. Oluwafemi at [email protected]
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Abstract

We herein report the detection of folic acid (FA) via the fluorometric method using water-soluble AgInS2 quantum dots (QDs). The optical analysis showed that the addition of FA to AgInS2 QDs results in significant, blue-shifted photoluminescence emission. A linear plot of the blueshift in the photoluminescence wavelength position against FA concentration was obtained in the range of 0.03–33 µM with the detection limit of 52 nM. Interference study showed the selective detection of FA in the presence of other biomolecules. The as-synthesized AgInS2 QDs can be employed as an optical sensor for the rapid detection of FA in aqueous solutions.

Type
Research Letters
Information
MRS Communications , Volume 9 , Issue 4 , December 2019 , pp. 1306 - 1310
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Copyright
Copyright © Materials Research Society 2019

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