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Dose Limited Resolution
Published online by Cambridge University Press: 02 July 2020
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1. Introduction
The definition of resolution as introduced by Lord Rayleigh [1] is related to the width of the point spread function of the imaging device. In this definition, noise has not been taken into account. Another definition of resolution has been introduced by Rose [2] in the field of radar and TV. Here the resolution is defined in terms of the dose (D) (i.e. number of imaging particles per unit area) and the signal to noise ratio SNR (i.e. the minimal contrast) A third definition of resolution is based on the idea that the microscope is a communication channel between the object and the observer. The resolution can then be rephrased as the amount of information that is transmitted by the channel in the sense as defined by Shannon [3] as a number of bits per unit area. This definition however does not describe how this information can be deduced and what its precision is.
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