Herpes Simplex Virus Infection in Pregnancy

doi:10.1017/9781108975780.073

Chapter 61 - Herpes Simplex Virus Infection in Pregnancy

from Section 11 - Infectious Conditions in Pregnancy

Published online by Cambridge University Press: 23 February 2023

Amira El-Messidi

Edited by

Amira El-Messidi and

Alan D. Cameron

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Amira El-Messidi: Affiliation:
McGill University, Montréal
Alan D. Cameron: Affiliation:
University of Glasgow

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Summary

A 23-year-old primigravida is referred for consultation at 21+5 weeks’ gestation with a new onset of genital lesions. Her referring physician informs you that she has no history of genital herpes and that her obstetric progress has been unremarkable. All routine prenatal screening tests and investigations have been normal. She has no obstetric complaints and indicates the fetus is active.

Keywords

Herpes simplex virus, pregnancy Primary, nonprimary, recurrent genital herpes simplex infection Risk factors Diagnosis, investigations Prenatal counseling Mother-to-child, perinatal transmission Antepartum, intrapartum, postpartum management Treatment, pharmacology Drug mechanism of action Neonatal herpes simplex infection Obstetric delivery Rupture of membranes Newborn care, breastfeeding

Type: Chapter
Information: OSCEs in Obstetrics and Maternal-Fetal Medicine
An Evidence-Based Approach
, pp. 787 - 795

DOI: https://doi.org/10.1017/9781108975780.073 [Opens in a new window]

Publisher: Cambridge University Press

Print publication year: 2023

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References

Suggested Readings

American College of Obstetricians and Gynecologists' Committee on Practice Bulletins – Obstetrics. Management of genital herpes in pregnancy: ACOG Practice Bulletin, No. 220. Obstet Gynecol. 2020;135(5):e193–e202.CrossRef Google Scholar

Canadian guidelines on sexually transmitted infections – management and treatment of specific infections – genital herpes simplex virus (HSV) infections. Available at www.canada.ca/en/public-health/services/infectious-diseases/sexual-health-sexually-transmitted-infections/canadian-guidelines/sexually-transmitted-infections/canadian-guidelines-sexually-transmitted-infections-32.html. Accessed August 27, 2020.Google Scholar

Centers for Disease Control and Prevention. Sexually transmitted diseases treatment guidelines, 2015. Available at www.cdc.gov/std/tg2015/genital-ulcers.htm. Accessed August 29, 2020.Google Scholar

Feltner, C, Grodensky, C, Ebel, C, et al. serologic screening for genital herpes: an updated evidence report and systematic review for the US Preventive Services Task Force. JAMA. 2016;316(23):2531–2543.CrossRef Google Scholar PubMed

Foley, E, Clarke, E, Beckett, VA, et al. Guideline: management of genital herpes in pregnancy. R Coll Obstet Gynaecol 2014. Available at www.rcog.org.uk/globalassets/documents/guidelines/management-genital-herpes.pdf. Accessed August 27, 2020.Google Scholar

Hollier, LM, Wendel, GD. Third trimester antiviral prophylaxis for preventing maternal genital herpes simplex virus (HSV) recurrences and neonatal infection. Cochrane Database Syst Rev. 2008;(1):CD004946.Google Scholar

Lee, R, Nair, M. Diagnosis and treatment of herpes simplex 1 virus infection in pregnancy. Obstet Med. 2017;10(2):58–60.CrossRef Google Scholar PubMed

Money, DM, Steben, M. No. 208 – guidelines for the management of herpes simplex virus in pregnancy. J Obstet Gynaecol Can. 2017;39(8): e199–e205.Google Scholar

Patel, R, Kennedy, OJ, Clarke, E, et al. 2017 European guidelines for the management of genital herpes. Int J STD AIDS. 2017;28(14):1366–1379.CrossRef Google Scholar PubMed

Stephenson-Famy, A, Gardella, C. Herpes simplex virus infection during pregnancy. Obstet Gynecol Clin North Am. 2014;41(4):601–614.Google Scholar