Book contents
- 50 Big Debates in Reproductive Medicine
- Series page
- 50 Big Debates in Reproductive Medicine
- Copyright page
- Contents
- Contributors
- Foreword
- Introduction
- Section I Limits for IVF
- Section II IVF Add-ons
- Section III The Best Policy
- Section IV Embryology
- 24A ICSI Should Be Used for All IVF Cycles
- 24B ICSI Should Be Used for All IVF Cycles
- 25A Embryo Morphokinetic Analysis (Time-Lapse Imaging) Is Helpful in Selecting Euploid Blastocysts
- 25B Embryo Morphokinetic Analysis (Time-Lapse Imaging) Is Helpful in Selecting Euploid Blastocysts
- 26A Time-Lapse Imaging Should Be a Routine Procedure in Clinical Embryology
- 26B Time-Lapse Imaging Should Be a Routine Procedure in Clinical Embryology
- 27A Artificial Intelligence Is Useful for Embryo Selection in IVF
- 27B Artificial Intelligence Is Useful for Embryo Selection in IVF
- 28A There Is No Need to Take Embryos Out of the Incubator until the Day of Embryo Transfer
- 28B There Is No Need to Take Embryos Out of the Incubator until the Day of Embryo Transfer
- 29A Blastocyst Culture Should Be a Routine in All IVF Cycles
- 29B Blastocyst Culture Should Be a Routine in All IVF Cycles
- Section V Ethics and Statistics
- Section VI Male-factor Infertility
- Section VII Genetics
- Section VIII Ovarian Stimulation
- Section IX Hormones and the Environment
- Index
- References
28B - There Is No Need to Take Embryos Out of the Incubator until the Day of Embryo Transfer
Against
from Section IV - Embryology
Published online by Cambridge University Press: 25 November 2021
Book contents
- 50 Big Debates in Reproductive Medicine
- Series page
- 50 Big Debates in Reproductive Medicine
- Copyright page
- Contents
- Contributors
- Foreword
- Introduction
- Section I Limits for IVF
- Section II IVF Add-ons
- Section III The Best Policy
- Section IV Embryology
- 24A ICSI Should Be Used for All IVF Cycles
- 24B ICSI Should Be Used for All IVF Cycles
- 25A Embryo Morphokinetic Analysis (Time-Lapse Imaging) Is Helpful in Selecting Euploid Blastocysts
- 25B Embryo Morphokinetic Analysis (Time-Lapse Imaging) Is Helpful in Selecting Euploid Blastocysts
- 26A Time-Lapse Imaging Should Be a Routine Procedure in Clinical Embryology
- 26B Time-Lapse Imaging Should Be a Routine Procedure in Clinical Embryology
- 27A Artificial Intelligence Is Useful for Embryo Selection in IVF
- 27B Artificial Intelligence Is Useful for Embryo Selection in IVF
- 28A There Is No Need to Take Embryos Out of the Incubator until the Day of Embryo Transfer
- 28B There Is No Need to Take Embryos Out of the Incubator until the Day of Embryo Transfer
- 29A Blastocyst Culture Should Be a Routine in All IVF Cycles
- 29B Blastocyst Culture Should Be a Routine in All IVF Cycles
- Section V Ethics and Statistics
- Section VI Male-factor Infertility
- Section VII Genetics
- Section VIII Ovarian Stimulation
- Section IX Hormones and the Environment
- Index
- References
Summary
With new time-lapse technology and the use of single-step media, embryos may increasingly remain undisturbed in culture during the process of IVF. Is there still a need for embryos to be removed from the incubator before the day of transfer? Is it better for an embryo to be left in single-step media, or is it beneficial to refresh the culture media on day three? With the potential need for assisted hatching prior to biopsy, or movement into fresh culture media, there are clear cases where any embryo may need to be taken out of the incubator. The technology of assisted reproduction may change the exact role of the embryologist, but observation, manipulation and maintenance of the culture environment remain vital.
- Type
- Chapter
- Information
- 50 Big Debates in Reproductive Medicine , pp. 149 - 150Publisher: Cambridge University PressPrint publication year: 2021
References
Mascarenhas, M, Fox, SJ, Thompson, K, Balen, AH. Cumulative live birth rates and perinatal outcomes with the use of time-lapse imaging incubators for embryo culture: a retrospective cohort study of 1882 ART cycles. BJOG 2019;126(2):280–86.CrossRefGoogle ScholarPubMed
ESHRE Working Group on Time-Lapse Technology: Apter, S, Ebner, T, Freour, T, et al. Good practice recommendations for the use of time-lapse technology. Hum Reprod Open. 2020;2020: Issue 2.CrossRefGoogle ScholarPubMed
Singh, S, Hobeika, E, Knochenhauer, ES, Traub, ML. Pregnancy rates after pre-implantation genetic screening for aneuploidy are only superior when trophectoderm biopsy is performed on hatching embryos. JARG. 2019;36(4):621–8.Google ScholarPubMed
Swain, J. Controversies in ART: considerations and risks for uninterrupted embryo culture. RMBO. 2019:39(1):19–26.Google ScholarPubMed
Sfontouris, IA, Martins, WP, Nastri, CO, et al. Blastocyst culture using single versus sequential media in clinical IVF: a systematic review and meta-analysis of randomized controlled trials. JARG. 2016;33(10):1261–72.Google ScholarPubMed