Book contents
- 50 Big Debates in Reproductive Medicine
- Series page
- 50 Big Debates in Reproductive Medicine
- Copyright page
- Contents
- Contributors
- Foreword
- Introduction
- Section I Limits for IVF
- Section II IVF Add-ons
- Section III The Best Policy
- Section IV Embryology
- Section V Ethics and Statistics
- Section VI Male-factor Infertility
- Section VII Genetics
- Section VIII Ovarian Stimulation
- Section IX Hormones and the Environment
- 45A Metformin Is an Effective Treatment for Infertility Associated with Anovulatory PCOS
- 45B Metformin Is an Effective Treatment for Infertility Associated with Anovulatory PCOS
- 46A Laparoscopic Ovarian Drilling Should Be Performed for CC-Resistant PCOS
- 46B Laparoscopic Ovarian Drilling Should Be Performed for CC-Resistant PCOS
- 47A Asymptomatic Polycystic Ultrasound Appearance of the Ovary Is Favourable for IVF Outcome
- 47B Asymptomatic Polycystic Ultrasound Appearance of the Ovary Is Favourable for IVF Outcome
- 48A Ultrasound Monitoring Is Not Required for Letrozole Treatment
- 48B Ultrasound Monitoring Is Not Required for Letrozole Treatment
- 49A Progesterone Levels Should Be Measured on the Day of hCG Administration
- 49B Progesterone Levels Should Be Measured on the Day of hCG Administration
- 50A Progesterone Treatment Does Not Help Recurrent Miscarriage Patients
- 50B Progesterone Treatment Does Not Help Recurrent Miscarriage Patients
- 51A The Microbiome Environment Influences IVF Results
- 51B The Microbiome Environment Influences IVF Results
- Index
- References
46A - Laparoscopic Ovarian Drilling Should Be Performed for CC-Resistant PCOS
For
from Section IX - Hormones and the Environment
Published online by Cambridge University Press: 25 November 2021
Book contents
- 50 Big Debates in Reproductive Medicine
- Series page
- 50 Big Debates in Reproductive Medicine
- Copyright page
- Contents
- Contributors
- Foreword
- Introduction
- Section I Limits for IVF
- Section II IVF Add-ons
- Section III The Best Policy
- Section IV Embryology
- Section V Ethics and Statistics
- Section VI Male-factor Infertility
- Section VII Genetics
- Section VIII Ovarian Stimulation
- Section IX Hormones and the Environment
- 45A Metformin Is an Effective Treatment for Infertility Associated with Anovulatory PCOS
- 45B Metformin Is an Effective Treatment for Infertility Associated with Anovulatory PCOS
- 46A Laparoscopic Ovarian Drilling Should Be Performed for CC-Resistant PCOS
- 46B Laparoscopic Ovarian Drilling Should Be Performed for CC-Resistant PCOS
- 47A Asymptomatic Polycystic Ultrasound Appearance of the Ovary Is Favourable for IVF Outcome
- 47B Asymptomatic Polycystic Ultrasound Appearance of the Ovary Is Favourable for IVF Outcome
- 48A Ultrasound Monitoring Is Not Required for Letrozole Treatment
- 48B Ultrasound Monitoring Is Not Required for Letrozole Treatment
- 49A Progesterone Levels Should Be Measured on the Day of hCG Administration
- 49B Progesterone Levels Should Be Measured on the Day of hCG Administration
- 50A Progesterone Treatment Does Not Help Recurrent Miscarriage Patients
- 50B Progesterone Treatment Does Not Help Recurrent Miscarriage Patients
- 51A The Microbiome Environment Influences IVF Results
- 51B The Microbiome Environment Influences IVF Results
- Index
- References
Summary
Oral ovulation medications such as clomiphene citrate (CC) and letrozole successfully induce ovulation in up to 80% of infertile women with PCOS. In the 20% of women who do not respond, second line therapies can include a combination of oral agents, gonadotropin ovulation induction, IVF or laparoscopic ovarian drilling (LOD). All second line therapies seem equally effective, however LOD may be simpler in that it is a one-time procedure, less expensive, more accessible to women who live in remote settings and does not increase the risk of multiple pregnancies. It should remain in the armamentarium of clinicians who manage subfertile women with PCOS.
- Type
- Chapter
- Information
- 50 Big Debates in Reproductive Medicine , pp. 239 - 241Publisher: Cambridge University PressPrint publication year: 2021
References
Teede, HJ, Misso, ML, Costello, MF, et al. International PCOS Network Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome Hum Reprod. 2018;33(9):1602–18.CrossRefGoogle ScholarPubMed
Gjönnaess, H. Polycystic ovarian syndrome treated by ovarian electrocautery through the laparoscope. Fertil Steril. 1984;41:20–5.CrossRefGoogle ScholarPubMed
Farquhar, C, Brown, J, Marjoribanks, J. Laparoscopic drilling by diathermy or laser for ovulation induction in anovulatory polycystic ovary syndrome. Cochrane Database Syst Rev. 2012;23:CD001122.Google Scholar
Bordewijk, EM, Ng, KYB, Rakic, L, et al. Laparoscopic ovarian drilling for ovulation induction in women with anovulatory polycystic ovary syndrome. Cochrane Database Syst Rev. 2020, 2. Art. No.: CD001122.CrossRefGoogle Scholar